Products
Silica Gel / Prep LC
Dynamic Adsorbents, Inc. silica gels are
carefully manufactured and quality assured to provide the ideal
laboratory and pilot Process chromatographic material. We control the
manufacturing process from raw material to finished product. We
carefully control the physical characteristics of pore size, surface
area, particle size and surface chemistry ensuring reproducible
optimized chromatographic behavior for:
k' - uniform
capacity - reproducible selectivity
RS- improved resolution N - excellent performance
Reproducible performance is delivered
regardless of the technique used, especially when transferring from one
technique to another.
|
Technique |
Application |
|
“Flash”
Chromatography Column Chromatography DCC - Dry Column Chromatography Large Column Chromatography TLC, HPTLC, HPLC |
Prep LC.
Request “Flash”, DCC, Application Guide(s)
Pilot -
Prep - Process Analytical QC Methods Development |
Flash
Chromatography
“Flash
chromatography" is a rapid form of preparative column chromatography -
prep
LC based upon “an air pressure driven hybrid of medium and short column
chromatography optimized for rapid separation.” This approach was pioneered
by W.C. Still at Columbia University, and described in J. Org Chem 43, 2923
(1978). Separation was based upon the relatively inexpensive apparatus used.
Flash
chromatography is typically used to prepare 0.1-10.0 g of material in less
than 15 minutes and is especially useful when the differences on TLC are
greater than 0.15 Rf units. Clearly, Flash chromatography is a simple and
economical approach to Prep LC.
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